supplements:
polyphenols, green tea – EGCG, lycopene, curcumine, Vitamin C
Brain:
CBD?
Heart
Toxicology tests
for MPTP or similar drag exposure
Glutathion
Magnesium
www.naturalstacks.com/blogs/news/magnesium
www.naturalnews.com/046401_magnesium_dietary_supplements_nutrient_absorption.html
magnesium deficiency can cause hreart palpatation and also calcification of heart and blood vessle
general association between magnesium and heart health www.ncbi.nlm.nih.gov/pmc/articles/PMC3957229/
magnesium salts could reduce the progress of aortic valve stenosis
Forced exercise 35% improvement, motor learning ? upregulate dopamine
www.ncbi.nlm.nih.gov/pubmed/19131578/
www.ncbi.nlm.nih.gov/pmc/articles/PMC4744893/#s002
motor learning activated by stressor – speed, to adapt to the stressor,result is speed and performance when in speed
i assume it goes both ways and e.g. Zen meditation will slow onedown, also depresion/LH/static job
possible treatment -external speed (treadmill),external speed /pulse measurement
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I speculate that high intensity over continues period of time develops (up regulate) dopamine secretion. that includes brain games
Exercise enhanced Neuroplasticity
Insulin Resistance, GLP-1 analogues, Incretin Mimetics for AD and PD
Brain
AD – See Bredesen
PD –
A pilot study in PD patients testing a GLP-1 receptor agonist that is currently on the market as a treatment for type 2 diabetes (exendin-4, Byetta) also showed encouraging effects. Several other clinical trials are currently ongoing in AD patients, testing another GLP-1 analogue that is on the market (liraglutide, Victoza). Recently, a third GLP-1 receptor agonist has been brought to the market in Europe (Lixisenatide, Lyxumia), which also shows very promising neuroprotective effects. This review will summarise the range of these protective effects that those drugs have demonstrated. GLP-1 analogues show promise in providing novel treatments that may be protective or even regenerative in AD and PD, something that no current drug does.
Drugs developed for treatment of diabetes show protective effects in Alzheimer’s and Parkinson’s diseases.
www.ncbi.nlm.nih.gov/pubmed/28927992
חקייני אינקרטין (Incretin Mimetics)
Heart:
Gut
See Ronda Patrick
related treatment option for PD see https://1.getmanaged.online/nly01-halts-pd/
NLY01 halts PD
Similar drugs to NLY01 already approved by the Food and Drug Administration for the treatment of type 2 diabetes include exenatide, lixisenatide, liraglutide and dulaglutide, each of which can cost approximately $2,000 for a 90-day supply. NLY01 is a long-acting drug with improved the brain penetration compared to these approved drugs for diabetes.
www.sciencedaily.com/releases/2018/07/180702120505.htm
afforable:
dir.indiamart.com/impcat/liraglutide.html
Herbs for PD
Oral hygiene – oil pulling coconut oil, adding ginger and lavender
oil pulling suggested by Bredesen to prevent bactermia
ginger and lavender anecdotal evidence
neuroprotective effect of nicotine and coffee in PD and AD
Dr Andrue Huberman – Nicotine can hold off certain types of PD and AD, and it also increase neuroplacticity
www.youtube.com/shorts/P1I-gHB8Ucc
more information:
Neuroprotective effect of nicotine
A meta-analysis of coffee drinking, cigarette smoking, and the risk of Parkinson’s disease.
Modifiable Risk Factors of Parkinson’s Disease (multiple studies)
byu/magic-theater inCholinergicHypothesis
Chronic heavy metal toxicity
Infection by Prion-like infection α-synuclein
from food:
www.ncbi.nlm.nih.gov/pmc/articles/PMC5701169/
- so human source probably also possible
- leaky gut probably a factor
Root Canal
Caffeine
www.ncbi.nlm.nih.gov/pmc/articles/PMC5942142/
www.ncbi.nlm.nih.gov/pmc/articles/PMC5942142/
dosage 1 gr per liter of drinking water
The neuroprotective effect of coenzyme Q(10) (CoQ(10))
MPTP
Cyrex Arrey
3 – leaky gut
Longevity diet + Long fast (fmd), Intermintent fasting 5:2 16:8
vegetarian, no sugar, good oils, low protein, small fish
see chapter 4 in the book
FMD – file 28 longevity diet audiobook
research by longo regarding many conditions that benefit from periodic fasting
homemade FMD:
Dr Mattson research and recommendations 5:2 and 16:8
According to research conducted by neuroscientist Mark Mattson and others, cutting your energy intake by fasting several days a week might help your brain ward off neurodegenerative diseases like Alzheimer’s and Parkinson’s while at the same time improving memory and mood.
5:2 diet…every time you eat, glucose is stored in your liver as glycogen, which takes about 10 to 12 hours to be depleted. After the glycogen is used up, your body starts burning fats, which are converted to ketone bodies, acidic chemicals used by neurons as energy. Ketones promote positive changes in the structure of synapses important for learning, memory, and overall brain health. But if you eat three meals a day with snacks between, your body doesn’t have the chance to deplete the glycogen stores in your liver, and the ketones aren’t produced. Mattson says exercise can also get your body to lower its glycogen levels, and not coincidentally, exercise has been shown to have the same positive effects on brain health as fasting.
5:2 diet…when the brain is challenged by physical exertion, cognitive tasks, or caloric restriction, the body produces a protein called BDNF (brain-derived neurotrophic factor), which not only strengthens neural connections and increases the production of new neurons but can also have an anti-depressive effect.
see also Dr Fung on treating insulin resistance with low carb + fasting