Anytime you take more than one drug simultaneously there is a danger that the drugs will cause adverse side effects, cancel each other out or change the effectiveness of each drug. This is a major risk and although most drug interactions are not serious there can be dire consequences. It is not just a case of drug-with-drug interaction but also a risk of drug-with food/beverage interaction, for example, you will often see a warning on prescription drugs to “avoid grapefruit juice.” There are also drug-with disease interactions that should be avoided. Check whether the drugs you are taking interact adversely with each other, with the food you are consuming, or with the condition you have.
Source: Drug Interactions Checker -Food/Supplement Interaction Checker