Radical new therapy for Parkinson’s will use stem cell transplants

Lab-grown nerve cells will replace those destroyed by disease – scientists hope treatment may be available in five years

Source: Radical new therapy for Parkinson’s will use stem cell transplants

STEM-PD trial 2024, 1 year after 4 succesful transpalnts out of for, now major side effects, and 4 more transplants done with higher dose, they will monitor the outcome for 3 years

STEM-PD, a cell-replacement trial for Parkinson’s, releases latest update

10 Health Benefits of Low-Carb and Ketogenic Diets

Many studies show that low-carb and ketogenic diets can lead to dramatic weight loss and improve most major risk factors for heart disease and diabetes. Also, repeatedly shown (but not always) to help with or reverse PD and other neurologicsal conditions

 

Source: 10 Health Benefits of Low-Carb an

Oral Glutamine Increases Circulating GLP-1, Glucagon and Insulin Levels in Lean, Obese and Type 2 Diabetic Subjects

Glutamine effectively increases circulating GLP-1, GIP and insulin levels in vivo and may represent a novel therapeutic approach to stimulating insulin secretion in obesity and type 2 diabetes.

Keywords: GLP-1, GIP, glucagon, insulin secretion, glutamine

Source: Oral Glutamine Increases Circulating GLP-1, Glucagon and Insulin Levels in Lean, Obese and Type 2 Diabetic Subjects

probiotics Bacillus subtilis PXN® 21® eliminates alpha-synuclein aggregates, possible PD treatment

Article in Cell megazine:
www.cell.com/cell-reports/fulltext/S2211-1247(19)31743-7?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124719317437%3Fshowall%3Dtrue

where to buy:

www.bio-kult.com/aboutmigrea

Magnesium to prevent and reverse Aurtic stenosis and calcification in general

the SEM data show that the protein-protein cross-linking bonds are the starting sites of calcification. In addition, substitution of Ca2+ cations by Mg2+ cations leads to the formation of amorphous hydroxyapatite, preventing aortic valve stenosis, which suggests that treatment with magnesium salts may reduce stenosis of aortic valves…
iv.iiarjournals.org/content/28/1/91.full

We observed strong, favorable associations between higher self-reported total (dietary and supplemental) magnesium intake and lower calcification of the coronary arteries…
www.ncbi.nlm.nih.gov/pmc/articles/PMC3957229/

Studies showed that a calcium to magnesium intake ratio <2.8 is critical for optimal health, supporting a long-held but non–evidence-based recommendation that the calcium to magnesium ratio should be close to 2. Increasing calcium intakes in the United States since 1977 have resulted in a calcium to magnesium ratio >3.0 since 2000, coinciding with increasing rates of T2D and colorectal cancer. US studies assessing oral magnesium therapy or dietary magnesium intakes showed beneficial effects of dietary magnesium in CVD, T2D, and cancers, although similar studies in populations with lower calcium to magnesium ratios (≥1.7) reported the opposite…
www.ncbi.nlm.nih.gov/pmc/articles/PMC4717874/

 

Fetal tissue implant – Wikipedia

Source: Fetal tissue implant – Wikipedia

…In 1982, seven people in Santa Clara County, California were diagnosed with Parkinsonism after having used MPPP contaminated with MPTP. In 1992, two of the seven patients were successfully treated at Lund University Hospital in Sweden with neural grafts of fetal tissue. One patient, who had been essentially paralyzed, regained enough motor function to ride a bicycle.[1]

NLY01 halts PD

Similar drugs to NLY01 already approved by the Food and Drug Administration for the treatment of type 2 diabetes include exenatide, lixisenatide, liraglutide and dulaglutide, each of which can cost approximately $2,000 for a 90-day supply. NLY01 is a long-acting drug with improved the brain penetration compared to these approved drugs for diabetes.

www.sciencedaily.com/releases/2018/07/180702120505.htm

afforable:
dir.indiamart.com/impcat/liraglutide.html

Longevity diet + Long fast (fmd), Intermintent fasting 5:2 16:8

vegetarian, no sugar, good oils, low protein, small fish

FMD see >>

see chapter 4 in the book

FMD –  file 28 longevity diet audiobook

research by longo regarding many conditions that benefit from periodic fasting

homemade FMD:

My Experience with the 5-Day Fasting Mimicking Diet


Dr Mattson research and recommendations 5:2 and 16:8

According to research conducted by neuroscientist Mark Mattson and others, cutting your energy intake by fasting several days a week might help your brain ward off neurodegenerative diseases like Alzheimer’s and Parkinson’s while at the same time improving memory and mood.

5:2 diet…every time you eat, glucose is stored in your liver as glycogen, which takes about 10 to 12 hours to be depleted. After the glycogen is used up, your body starts burning fats, which are converted to ketone bodies, acidic chemicals used by neurons as energy. Ketones promote positive changes in the structure of synapses important for learning, memory, and overall brain health. But if you eat three meals a day with snacks between, your body doesn’t have the chance to deplete the glycogen stores in your liver, and the ketones aren’t produced. Mattson says exercise can also get your body to lower its glycogen levels, and not coincidentally, exercise has been shown to have the same positive effects on brain health as fasting.

5:2 diet…when the brain is challenged by physical exertion, cognitive tasks, or caloric restriction, the body produces a protein called BDNF (brain-derived neurotrophic factor), which not only strengthens neural connections and increases the production of new neurons but can also have an anti-depressive effect.


see also Dr Fung on treating insulin resistance with low carb + fasting

IDM Program