Could Creating a Healthy Gut Using FMD Prevent or Treat PD?

A 2018 study published by the NIH looked at neuroprotection of the fasting mimicking diet (FMD) on MPTP-induced PD mice via gut microbiota and metabolites. During the study the mice were put on a diet of fasting 3 days followed by 4 days of refeeding for three 1-week cycles. This accelerated the retention of motor function and attenuated the loss of dopaminergic neurons in the substantia nigra in 1-methyl-4-phenyl-1,2,3,6-tetrathydropyridine (MPTP)-induced PD mice. The findings demonstrated that FMD can be a new means of preventing and treating PD through promoting a favorable gut microbiota composition and metabolites.

Source: Neuroprotection of Fasting Mimicking Diet on MPTP-Induced Parkinson’s Disease Mice via Gut Microbiota and Metabolites – PubMed