How the gut microbiome affects Parkinson’s disease remains unclear. Goya et al. showthat the probiotic B. subtilis strain PXN21 inhibits and clears α-synuclein aggregationin a C. elegans model. The bacterium acts via metabolites and biofilm formation toactivate protective pathways in the host, including DAF-16/FOXO and sphingolipid metabolism.
Source: Probiotic Bacillus subtilis Protects against α-Synuclein Aggregation in C. elegans: Cell Reports
so, if this probiotics eat alpha-synuclein aggregations (oligomers) in the gut (assuming there is reabsorption issue, otherwise how cares) , and if sweating secreats alpha-synuclein, those are to ways to reduce or normalize alpha-synuclein levels in the body