Currently, there is no conclusive evidence about the effectiveness and efficacy of HMs on PD. For establishing clinical evidence of HMs on PD, rigorous RCTs with sufficient statistical power should be promoted in future.
Could Parkinson’s be Caused by Infection?
In examining the hypothesis that PD could stem from an influenza virus infection that develops into encephalitis lethargica the role of bacterial and viral infections as a possible cause of Parkinsonism is questioned. The paper compares the clinical, histological, and structural features of Parkinsonism in infectious diseases and looks at the influenza virus and why and how it became associated with PD. Herpes Simplex Virus 1; Epstein-Barr Virus; Varicella-Zoster Virus; Hepatitis C; the Japanese Encephalitis Virus and the West Nile Virus are discussed in connection with PD. The review also examines the Human Immunodeficiency Virus (HIV) and Parkinsonism. In conclusion, the synergistic effect of infectious pathogens in inducing neuroinflammation leading to PD development has been observed. However, it cannot be established that all cases of PD are associated with increased inflammation and underlying chronic infection. Further research is necessary to examine the involvement and extent to which pathogens and inflammatory cytokines play in the pathomechanism of PD.
Source: Infectious Etiologies of Parkinsonism: Pathomechanisms and Clinical Implications
Megadose Vitamin C – As An Antiviral Treatment
A study published by the NIH Clinical Trials looked at vitamin C infusion as a possible treatment for severe COVID-infected pneumonia. The study was sponsored by ZhiYong Peng of the Zhongnan Hospital. The study hypothesized that vitamin C infusion could improve the prognosis of SARI (Severe acute respiratory infection)patients. 12g vitamin C was infused in the experimental group twice a day for 7 days by the infusion pump with a speed of 12ml/h. Early clinical studies have shown that vitamin C can effectively prevent the cytokine surge caused by sepsis, and neutrophils accumulation in the lungs destroying alveolar capillaries. In addition, vitamin C can help to eliminate alveolar fluid by preventing the activation and accumulation of neutrophils, and reducing alveolar epithelial water channel damage. At the same time, vitamin C can prevent the formation of neutrophil extracellular traps and shorten the duration of the common cold. In a controlled but non-randomized trial, 85% of the 252 students treated experienced a reduction in symptoms in the high-dose vitamin C group (1g / h at the beginning of symptoms for 6h, followed by 3 * 1g / day). Among patients with sepsis and ARDS, patients in the high-dose vitamin group did not show a better prognosis and other clinical outcomes.
Source: Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected Pneumonia
Herbal Antivirals